內容介紹：

(最新補充, 9th Feb. 2005)
Germline development is one of the most important topics
of developmental biology, given that an embryo is derived from a
germ cell. In the second term of 2003, there were six students
attending this course. Although I tried to explain from the very
basic of developmental biology in general, yet undergraduate
students without Biochemistry or Cell biology background felt difficult
to catch up my lecturing content. Accordingly, this year I modify the
scheme of my teaching in particular for post-graduate students who are
highly interested in germline development.



(原有內容)
本課程之主旨在於啟發學生對生殖細胞發育的興趣，解析生殖細胞發育的機制，並訓練對當代重要
研究結果之數據判讀。

課程大綱：
1. Principle of germline development (I): germ-cell specification
2. Principle of germline development (II): germ-cell migration
3. Principle of germline development (III): germ-cell
differentiation
4. Germline development in the fly Drosophila melanogaster
5. Germline development in the worm C.elegans
6. Germline development in the zebrafish Danio rerio
7. Germline development in the mouse Mus musculus and other mammals
8. Germline development in the non-model organisms
9. Molecular mechanisms of germ-cell specification
10.Molecular mechanisms of germ-cell migration
11.Molecular mechanisms of germ-cell differentiation
12.Studying germline development with functional-genomics
methodology

(上課方式):
Every topic includes lecture and paper presentation.

(成績評量): 期中考: 30%; 課堂報告: 40%; 期末書面報告: 30%.

教科書： N/A

參考書：
1. Principle of Development by Wolpert, L.
2. Developmental Biology by Scott F. Gilbert
3. Molecular Biology of the Cell by Bruce Alberts, et al
4. Germline Development - Symposium No. 182 by CIBA Foundation
Symposium